APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Dental Plaque ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011389
Disease: Dental Plaque
Dental Plaque 		0.010 Biomarker phenotype BEFREE Plaque pathology is not evident even when Aβ1-42 is increased by pharmacological manipulation (using calpain inhibitor 1), indicating that soluble Aβ species, or other APP processing products, are sufficient to cause the initial synaptic changes. 27287430 2016