APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023418
Disease: leukemia
leukemia 		0.030 GeneticVariation disease BEFREE Amyloid precursor protein cooperates with c-KIT mutation/overexpression to regulate cell apoptosis in AML1-ETO-positive leukemia via the PI3K/AKT signaling pathway. 27460334 2016
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease BEFREE Our study provides a novel clue that APP is involved in the extramedullary infiltration of leukemia by MMP-2. 23179400 2013
CUI: C0023418
Disease: leukemia
leukemia 		0.030 Biomarker disease LHGDN The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing. 15004329 2004