APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Metabolic Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.030 Biomarker group BEFREE Tissue-Specific Metabolomics Analysis Identifies the Liver as a Major Organ of Metabolic Disorders in Amyloid Precursor Protein/Presenilin 1 Mice of Alzheimer's Disease. 30592618 2019
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.030 Biomarker group BEFREE In this regard, 2-AAA could be a potential biomarker of obesity and obesity-related metabolic disorders. 31541119 2019
CUI: C0025517
Disease: Metabolic Diseases
Metabolic Diseases 		0.030 Biomarker group BEFREE This review presents the hypothesis that amyloidogenic processing of APP in peripheral tissues plays a key role in the response to nutrient excess and that this could contribute to the pathogenesis of metabolic diseases such as obesity and type 2 diabetes (T2D). 28349564 2017