APP, amyloid beta precursor protein, 351

N. diseases: 384; N. variants: 105
Disease: Gangliosidosis GM1 ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085131
Disease: Gangliosidosis GM1
Gangliosidosis GM1 		0.010 Biomarker disease BEFREE APP C-terminal fragments (APP-CTFs) were also increased in brains of the three mouse models; however, discrepancies between LC3-II and APP-CTFs were seen between primary (GM1 gangliosidosis and Sandhoff disease) and secondary (Niemann-Pick type C1) lysosomal storage models. 20864542 2010