APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Cerebrovascular Insufficiency ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0241832
Disease: Cerebrovascular Insufficiency
Cerebrovascular Insufficiency 		0.010 Biomarker disease BEFREE The soluble, highly toxic amyloid-β species, generated from the amyloidogenic processing of amyloid precursor protein, are known instigators of the chronic cerebrovascular insufficiency observed in both Alzheimer's disease patients and transgenic mouse models. 27339263 2017