APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Localized amyloidosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0268392
Disease: Localized amyloidosis
Localized amyloidosis 		0.010 Biomarker disease BEFREE It has not been determined if the Ig light chain (LC) amyloid precursor protein in localized amyloidosis is synthesized by circulating plasma cells with targeting of the amyloid fibril-forming process to one specific organ, or whether the synthesis of Ig LC and fibril formation occurs entirely as a localized process. 10228037 1999