APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Endothelial dysfunction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 Biomarker phenotype BEFREE Endothelium-specific amyloid precursor protein deficiency causes endothelial dysfunction in cerebral arteries. 28959912 2018
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 Biomarker phenotype BEFREE Our results suggest that impairment of α-processing and shift to amyloidogenic pathway of APP contribute to endothelial dysfunction induced by senescence. 29348391 2018
CUI: C0856169
Disease: Endothelial dysfunction
Endothelial dysfunction 		0.030 Biomarker phenotype BEFREE Plasma biomarkers such as matrix metalloproteinase-9, interleukin-6, high sensitive C-reactive protein, and amyloid β precursor protein (APP770, indicating endothelial dysfunction) were measured twice: (1) within 24 hours; and (2) 1 week after their admission. 29454567 2018