APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1861735
Disease: Dementia, familial Danish
Dementia, familial Danish
0.010 Biomarker disease BEFREE We show that inhibition of APP cleavage by β-secretase rescues synaptic/memory deficits in a mouse model of FDD. 22170863 2012