APRT, adenine phosphoribosyltransferase, 353

N. diseases: 384; N. variants: 12
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 AlteredExpression disease BEFREE Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy. 29394501 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 Biomarker disease BEFREE A potential strategy for treating atherosclerosis: improving endothelial function via AMP-activated protein kinase. 29675553 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 AlteredExpression disease BEFREE Here we report that the AMP-activated protein kinase α1 (AMPKα1) in monocytes promotes atherosclerosis by increasing monocyte differentiation and survival. 28330873 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 AlteredExpression disease BEFREE Liraglutide, a GLP-1 receptor agonist, inhibits vascular smooth muscle cell proliferation by enhancing AMP-activated protein kinase and cell cycle regulation, and delays atherosclerosis in ApoE deficient mice. 28445811 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 Biomarker disease BEFREE Phosphodiesterase 4D (PDE4D), through the regulation of cyclic AMP, modulates inflammation and other processes that affect atherosclerosis and stroke. 23863764 2013
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 AlteredExpression disease BEFREE Activation of AMP-activated protein kinase is required for berberine-induced reduction of atherosclerosis in mice: the role of uncoupling protein 2. 21980456 2011
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.070 AlteredExpression disease BEFREE This study investigated whether dysfunction of AMP-activated protein kinase (AMPK) causes aberrant ER stress and atherosclerosis in vivo. 20124121 2010