FAS, Fas cell surface death receptor, 355

N. diseases: 754; N. variants: 47
Disease: Bladder Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 GeneticVariation disease BEFREE Among the patients that received BCG immunotherapy, more FAS homozygous patients had BCa recurrence than FAS polymorphism-negative patients (P < 0.001) and more patients with homozygote FASL polymorphisms had BCa recurrence than those with heterozygous FASL polymorphisms and no polymorphism. 29453645 2018
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 GeneticVariation disease BEFREE Functional genetic variants in apoptosis-associated FAS and FASL genes and risk of bladder cancer in a Turkish population. 24815844 2015
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 Biomarker disease BEFREE Deregulation of FAS/FASL system may lead to immune escape and influence bacillus Calmette-Guérin (BCG) immunotherapy outcome, which is currently the gold standard adjuvant treatment for high-risk non-muscle invasive bladder tumors. 23948181 2014
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 Biomarker disease BEFREE Identification of a methylation hotspot in the death receptor Fas/CD95 in bladder cancer. 22076446 2012
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 GeneticVariation disease BEFREE FAS and FASLG polymorphisms appear to jointly contribute to risk of bladder cancer in this southern Chinese population. 16538171 2006
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 GeneticVariation disease BEFREE Three human bladder cancer lines (T24, J82, and 5637) were treated with the conventional Fas agonist CH-11, a monoclonal antibody to the Fas receptor. 15514684 2005
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 AlteredExpression disease BEFREE Expression of Fas protein and p53 status was studied by immunohistochemistry in 83 bladder cancer specimens. 14972509 2004
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.370 Biomarker disease CTD_human Doxorubicin sensitizes human bladder carcinoma cells to Fas-mediated cytotoxicity. 9070496 1997