|
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Malignant neoplasm of prostate
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study of prostate cancer in West African men.
|
24185611 |
2014 |
|
Solid Neoplasm
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
It was previously demonstrated that engineered mesenchymal stem cells (MSCs) which express a high level of a very efficient modified gene CYP2B6* (CYP2B6TM-RED) acting as a suicide gene (MSC-2B6*) in combination with cyclophosphamide (CPA) constitute a powerful cell/gene therapy approach for solid tumors.
|
31741770 |
2019 |
|
Solid Neoplasm
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
These data suggest that MSCs expressing CYP2B6TM-RED with CPA could represent a promising treatment for solid tumors to test in future clinical trials.
|
27565211 |
2016 |
|
Solid Neoplasm
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
These data suggest that combining the CYPB6TM-RED gene with CPA may hold promise as a highly effective treatment for solid tumors in humans.
|
24766134 |
2014 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Intratumoral injections of CYP2B6TM-RED-MSCs and CPA completely eradicated tumors in 33% of mice without recurrence after 6months.
|
27565211 |
2016 |
|
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
CYP/RED fusion proteins have never been previously expressed in mammalian cells, to enable expression the fusion protein was cloned into an adenoviral vector and subsequently several pulmonary tumor cell lines were infected.
|
15746946 |
2005 |
|
Anorexia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
</p> Results:In general, nutrition is experienced, not only by athletes themselves but also by technicians and coaches, as a tool for improving performance and as such assimilated to an aspect of training but in the presence of factors of vulnerability towards the ED by of the young athletes the exaggerated tendency to manipulate the weight can determine the appearance of an eating disorder or of the so-called athletic anorexia or the RED-S. </p> Conclusions:It is important to emphasize that not only do professional athletes suffer from it, but also good-looking amateurs and amateurs.
|
31684854 |
2020 |
|
Eating Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
</p> Results:In general, nutrition is experienced, not only by athletes themselves but also by technicians and coaches, as a tool for improving performance and as such assimilated to an aspect of training but in the presence of factors of vulnerability towards the ED by of the young athletes the exaggerated tendency to manipulate the weight can determine the appearance of an eating disorder or of the so-called athletic anorexia or the RED-S. </p> Conclusions:It is important to emphasize that not only do professional athletes suffer from it, but also good-looking amateurs and amateurs.
|
31684854 |
2020 |
|
Craniofacial Dysostosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
From June 2013 to February 2015, a total of nine children with Crouzon syndrome underwent Le Fort III distraction osteogenesis with a rigid external distraction device (RED device, KLS Martin, Tuttlingen, Germany).
|
30642732 |
2019 |
|
Female Athlete Triad Syndrome
|
0.010 |
Biomarker
|
disease |
BEFREE |
Comparison of Female Athlete Triad Coalition and RED-S risk assessment tools.
|
31296115 |
2019 |
|
Steatohepatitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Liver histology revealed a remarkable reduction of steatosis in the HF + RED group, and Kupffer cell profiling displayed a marked switch towards the M2 phenotype.
|
31337415 |
2019 |
|
Craniofacial dysostosis type 1
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
From June 2013 to February 2015, a total of nine children with Crouzon syndrome underwent Le Fort III distraction osteogenesis with a rigid external distraction device (RED device, KLS Martin, Tuttlingen, Germany).
|
30642732 |
2019 |
|
Dental caries
|
0.010 |
Biomarker
|
disease |
BEFREE |
Binding kinetic analysis of piceatannol was performed using Octet RED against both GtfB and GtfC, which produced low micromolar <i>K</i><sub>D</sub> values.Piceatannol inhibited <i>S. mutans</i> colonization in an in vivo drosophila model and a rat model of dental caries.
|
30087944 |
2018 |
|
Liver neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
The goal of our study was to assess the feasibility and efficacy of intra-arterial administration of MSCs transduced with an optimized gene (MSC-CYP2B6TM-RED) followed by intravenous administration of cyclophosphamide (CPA) into the VX2 rabbit liver tumor.
|
29090347 |
2018 |
|
Tremor
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Shake flask design was found to affect undecylprodigiosin (RED, a marker of secondary metabolism) production; the RED yield was 12 and 385 times greater in conventional normal Erlenmeyer flasks (NF) than in baffled flasks (BF) and coiled flasks (CF), respectively.
|
30486842 |
2018 |
|
Duck viral enteritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
All recombinant viruses were constructed by using two-step of RED recombination system implemented on the duck plague virus Chinese virulent strain (DPV CHv) genome cloned into a bacterial artificial chromosome.
|
29511274 |
2018 |
|
Arthritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Recombinant Adeno-Associated Virus Expressing Truncated IK Cytokine Diminishes the Symptoms of Inflammatory Arthritis.
|
28683532 |
2017 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.010 |
Biomarker
|
disease |
BEFREE |
The RED-13 was also positively related to a diagnosis of type 2 diabetes as well as cravings for sweet and savory foods.
|
28611698 |
2017 |
|
Hepatitis E
|
0.010 |
Biomarker
|
disease |
BEFREE |
Presence of Hepatitis E Virus in a RED Deer (Cervus elaphus) Population in Central Italy.
|
25892400 |
2017 |
|
Brachial Plexus Neuritis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Patients with NA had significantly higher CSA2-values than controls (6.36±2.75vs.
|
28618294 |
2017 |
|
Neuralgic Amyotrophy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Patients with NA had significantly higher CSA2-values than controls (6.36±2.75vs.
|
28618294 |
2017 |
|
Overweight or obesity
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
In summary, the RED-13 is a brief self-report measure that broadly captures the spectrum of RRE and may be a useful tool for identifying individuals at risk for overweight or obesity.
|
28611698 |
2017 |
|
Color vision defect
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
We studied 247 Japanese males with congenital deutan color-vision deficiency and found that 37 subjects (15.0%) had a normal genotype of a single red gene followed by a green gene(s).
|
12626747 |
2003 |
|
Color blindness
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We studied 247 Japanese males with congenital deutan color-vision deficiency and found that 37 subjects (15.0%) had a normal genotype of a single red gene followed by a green gene(s).
|
12626747 |
2003 |