IK, IK cytokine, 3550

N. diseases: 23; N. variants: 5
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE It was previously demonstrated that engineered mesenchymal stem cells (MSCs) which express a high level of a very efficient modified gene CYP2B6* (CYP2B6TM-RED) acting as a suicide gene (MSC-2B6*) in combination with cyclophosphamide (CPA) constitute a powerful cell/gene therapy approach for solid tumors. 31741770 2019
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE These data suggest that MSCs expressing CYP2B6TM-RED with CPA could represent a promising treatment for solid tumors to test in future clinical trials. 27565211 2016
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE These data suggest that combining the CYPB6TM-RED gene with CPA may hold promise as a highly effective treatment for solid tumors in humans. 24766134 2014