|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to evaluate the association of the IL1A (-889) gene polymorphism in Brazilian individuals with different clinical forms of periodontitis and severity of disease.
|
17214636 |
2007 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore, we evaluated whether the IL-1 and FcgammaR gene polymorphisms represent a common risk factor for RA and periodontitis.
|
18052703 |
2007 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Therefore, we evaluated whether the combination of FcgammaR or IL-1 polymorphic genes represents a common risk factor for SLE and periodontitis.
|
17335370 |
2007 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
Therefore, we evaluated whether the IL-1 and FcgammaR gene polymorphisms represent a common risk factor for RA and periodontitis.
|
18052703 |
2007 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
LHGDN |
We report the relationship between type 2 diabetes, the IL-1A/1B haplotype, and periodontitis in a population-based study.
|
18315433 |
2008 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We report the relationship between type 2 diabetes, the IL-1A/1B haplotype, and periodontitis in a population-based study.
|
18315433 |
2008 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Previous reports of an association between IL1 promoter SNPs and periodontitis might reflect subpopulation effects and have to be interpreted with care.
|
18723088 |
2008 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
A total of 106 patients hospitalized with ACS or angina were compared to a group of 1,959 individuals tested for susceptibility to periodontitis by profiling the IL-1 gene.
|
18166103 |
2008 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Periodontitis-induced autoinflammatory response also may play a role in the development/severity of BD and RAS via IL-1 gene alteration.
|
17960403 |
2008 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to evaluate the impact of the composite IL-1 genotype (allele 2 at IL-1A -889 and IL-1B +3954) in the association between acute myocardial infarction (AMI) and periodontitis.
|
19563289 |
2009 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We evaluated the relationships among IL-1 gene polymorphisms, type 2 diabetes, and periodontitis.
|
19792847 |
2009 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
It is suggested that polymorphisms in the interleukin-1 (IL1) receptor antagonist gene have an important role in the susceptibility of the host to periodontitis.
|
20450372 |
2010 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No significant associations between polymorphism of the IL-1 gene and periodontitis or HIV infection were observed.
|
20027454 |
2010 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
This review article aimed to determine whether IL-1 could be regarded as a genetic marker for periodontitis by reviewing data concerning susceptibility, clinical parameters, and treatment strategies in relation to the IL-1 genotype.
|
20490394 |
2010 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms in the interleukin-1 (IL-1) gene cluster have been suggested to influence the pathogenesis of periodontitis.
|
21672595 |
2011 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Indicators of inflammation may be important clinical determinants of future periodontal disease progression, but the IL-1 genotype was not a risk indictor for early (slight) periodontitis as defined in this subject population.
|
21054222 |
2011 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
However the association between the carriage of the IL-1 rare alleles and periodontitis differed between the Down and non-Down subjects.
|
21712624 |
2011 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate if IL-1 gene cluster polymorphisms are associated with chronic (CP) and aggressive (AgP) periodontitis in a Jordanian population.
|
21035110 |
2011 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was investigate the association of functional IL1 gene polymorphisms and transcript levels with susceptibility to CKD and PD.
|
22795294 |
2012 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
One previous meta-analysis has been published on this topic and supported an association between IL-1 genes and periodontitis, but considerable doubt remains about the patient populations in which the association may be of clinical relevance.
|
22348697 |
2012 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Interleukin-1 (IL-1) is a potent proinflammatory cytokine that plays an essential role during the pathogenesis of periodontitis.
|
23592003 |
2013 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Using decision tree analysis, we identified the presence of bacterial species Tannerella forsythia, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and SNPs TNF -857 and IL-1A -889 as discriminators between periodontitis and non-periodontitis.
|
23100272 |
2013 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, we did confirm the previously suggested association between PO and IL1 gene cluster polymorphisms, and between PO and four common risk factors (coffee, smoking, alcohol and fizzy drinks) and one common protective factor (fish).
|
24275344 |
2014 |
|
Periodontitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Previous studies have indicated that type-1 and type-2 interleukin-1 (IL-1) receptors (IL-1R1 and IL-1R2) play important roles in periodontitis progression.
|
24818754 |
2014 |
|
Periodontitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to test if polymorphisms of genes of IL-1α(+4845) and IL-1β(+3954) were linked with periodontitis, in a case-control study population, delimited to a specific geographic area, in association with microbiological findings.
|
24843315 |
2014 |