IL1A, interleukin 1 alpha, 3552

N. diseases: 1002; N. variants: 19
Disease: Aortitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003509
Disease: Aortitis
Aortitis 		0.010 Biomarker disease BEFREE IL-25 enhanced IL-1β and TNF production by IL-25 receptor-expressing dendritic cells and macrophages, respectively, at inflammatory sites of aortae of Il1rn<sup>-/-</sup> mice, contributing to exacerbation of development of IL-1-, TNF- and IL-17A-dependent aortitis in those mice. 31745167 2019