IL1A, interleukin 1 alpha, 3552

N. diseases: 1002; N. variants: 19
Disease: Idiopathic recurrent pericarditis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4707790
Disease: Idiopathic recurrent pericarditis
Idiopathic recurrent pericarditis 		0.040 Biomarker disease BEFREE Due to the overlap between idiopathic recurrent pericarditis and auto-inflammatory diseases, there is growing evidence for utilizing IL-1 receptor antagonists in this condition. 31437316 2019
CUI: C4707790
Disease: Idiopathic recurrent pericarditis
Idiopathic recurrent pericarditis 		0.040 Biomarker disease BEFREE Indeed, two recent randomized controlled trials have shown that the IL-1 receptor antagonist anakinra is effective for the treatment of idiopathic recurrent pericarditis and the IL-1β blocking agent canakinumab is effective in reducing myocardial infarction in people at risk. 29904899 2018
CUI: C4707790
Disease: Idiopathic recurrent pericarditis
Idiopathic recurrent pericarditis 		0.040 Biomarker disease BEFREE Management of idiopathic recurrent pericarditis in adults and in children: a role for IL-1 receptor antagonism. 29633070 2018
CUI: C4707790
Disease: Idiopathic recurrent pericarditis
Idiopathic recurrent pericarditis 		0.040 AlteredExpression disease BEFREE Recent studies point at inhibition of IL-1 activity as an attractive treatment option for patients with refractory idiopathic recurrent pericarditis. 29910817 2018