IL1B, interleukin 1 beta, 3553

N. diseases: 1801; N. variants: 22
Disease: Anovulation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003128
Disease: Anovulation
Anovulation 		0.010 AlteredExpression phenotype BEFREE LOX overexpression was present in PCOS ovaries, due at least in part to interleukin-1β (IL-1β), and inhibition of LOX activity with β-aminopropionitrile (BAPN) ameliorated polycystic ovary morphology and anovulation. 30272163 2018