IL1R1, interleukin 1 receptor type 1, 3554

N. diseases: 184; N. variants: 40
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.030 Biomarker disease BEFREE We demonstrate that IL1R1-deficient mice are completely resistant to the effects of celastrol in leptin sensitization and treatment of obesity, diabetes, and nonalcoholic steatohepatitis. 30833749 2019
CUI: C0028754
Disease: Obesity
Obesity
0.030 Biomarker disease BEFREE In summary, IL1R1- and IL1β-related transcripts are elevated in the setting of obesity. 24458711 2014
CUI: C0028754
Disease: Obesity
Obesity
0.030 AlteredExpression disease BEFREE Adiponectin and IL-1 Ra levels might be better markers of the risk of obesity and type 2 diabetes than hs-CRP. 18386294 2008