IL1RN, interleukin 1 receptor antagonist, 3557

N. diseases: 701; N. variants: 52
Disease: Acute pancreatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.030 GeneticVariation disease BEFREE One intronic SNP (IL1RN -1129T>C, rs4251961) was significantly associated with the risk of AP (odds ratio, 0.304; 95% confidence interval, 0.095 to 0.967; p = 0.043). 29117667 2018
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.030 Biomarker disease BEFREE However, a predetermined imbalance between IL-1beta and its antagonist IL-1RA would appear to exist in patients with severe acute pancreatitis, although the genetic basis for this altered relationship could not be determined. 11331456 2001
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.030 Biomarker disease BEFREE IL-1RN appears to determine severity of acute pancreatitis and susceptibility to idiopathic acute pancreatitis. 10766448 2000