IL1RN, interleukin 1 receptor antagonist, 3557

N. diseases: 701; N. variants: 52
Disease: Schnitzler Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524988
Disease: Schnitzler Syndrome
Schnitzler Syndrome 		0.320 Biomarker disease BEFREE After 6 years, his worsening symptoms and abnormal investigations led to a rare diagnosis of Schnitzler's syndrome and a trial of the interleukin 1 receptor antagonist, anakinra, which caused a rapid and complete resolution of his symptoms. 31036740 2019
CUI: C0524988
Disease: Schnitzler Syndrome
Schnitzler Syndrome 		0.320 GeneticVariation disease BEFREE Here we describe the temporal relationship of serum hepcidin, serum iron and cytokines in a patient with HFE-related (C282Y homozygous) hereditary hemochromatosis who was treated for an auto-inflammatory condition, i.e. variant Schnitzler's syndrome, with the potent anti-inflammatory cytokine inter-leukin-1 receptor antagonist (IL-1ra, anakinra). 19608676 2009
CUI: C0524988
Disease: Schnitzler Syndrome
Schnitzler Syndrome 		0.320 Therapeutic disease CTD_human Beneficial response to anakinra and thalidomide in Schnitzler's syndrome. 16096327 2006