IL2RA, interleukin 2 receptor subunit alpha, 3559

N. diseases: 540; N. variants: 43
Disease: Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 Biomarker group BEFREE No correlation was found between the type of lymphoma and total soluble CD25 or IL2 independently. 31383650 2019
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 AlteredExpression group BEFREE ADCT-301 has highly potent and selective cytotoxicity against a panel of CD25-expressing human lymphoma cell lines. 27535974 2016
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 Biomarker group BEFREE Moreover, in mice, intrasplenic injection of IDO+ leukemia/ lymphoma A20 cells induces the expansion of bona fide T(reg) cells by conversion of CD4+CD25- T cells; this effect is counteracted by 1-MT treatment. 17164341 2007
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 Biomarker group BEFREE The lymphoma lesion additionally harbored CD3(+) CD25(+) activated normal T cells despite ongoing tumor progression. 11423937 2001
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 Biomarker group BEFREE These in vivo data indicate a possible clinical impact for patients with relapsed CD25- and/or CD30-positive lymphoma. 11029515 2000
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 AlteredExpression group BEFREE The immunophenotypical analysis of lymphoma revealed that the tumor expressed CD2, CD3, CD4, CD5, CD25 and HLA-DR. 7815138 1995
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.070 Biomarker group BEFREE However 3 cases of CD25-positive ML showed a dramatically higher density of IL-6 producing cells (70, 50, 43 producing cells per 10,000 cells, respectively) as compared to the other 9 cases of CD25-positive ML (mean 6.03 +/- 2.1 per 10,000). 1498262 1992