IL3, interleukin 3, 3562

N. diseases: 211; N. variants: 3
Disease: Refractory anemias ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.030 AlteredExpression disease BEFREE Only a few of the RA patients had synovial T cells with increased expression of mRNA for interleukin-3 (25%) and interferon-gamma (25%). 1462123 1992
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.030 GeneticVariation disease BEFREE Both conventional karyotyping and X-inactivation analysis demonstrated the persistence of a monoclonal pattern of hematopoiesis in the two patients with refractory anemia (RA) treated either with GM-CSF or with IL-3. 1676079 1991
CUI: C0002893
Disease: Refractory anemias
Refractory anemias 		0.030 Biomarker disease BEFREE Southern blot analysis of somatic cell hybrids retaining the normal or the deleted chromosome 5 from two patients with the refractory anemia 5q- syndrome indicated that IL-3 sequences were absent form the hybrids retaining the deleted chromosome 5 but not from hybrids that had a cytologically normal chromosome 5. 3497400 1987