IL4, interleukin 4, 3565

N. diseases: 996; N. variants: 23
Disease: Contracture of joint ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009918
Disease: Contracture of joint
Contracture of joint 		0.010 Biomarker disease BEFREE On the basis of our findings we conclude that the anti-inflammatory cytokine IL-4 specifically regulates viability and the contractile properties of MFs via up-regulating the gene expression of α-SMA and collagen type I. IL-4 may be a helpful target in developing anti-fibrotic therapeutics for post-traumatic joint contracture in human.© 2016 Orthopaedic Research Society. 27504740 2017