Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
Estriol: a potent regulator of TNF and IL-6 expression in a murine model of endotoxemia.
|
8979148 |
1996 |
Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
Expression of TNF alpha and IL-6 mRNA in the lung, spleen and heart and the circulating levels of these cytokines markedly increased in endotoxemia.
|
9081704 |
1997 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
We have tested directly the hypothesis that three cytokines (IL-1 beta, TNF alpha and IL-6) generated during endotoxaemia affect venous tone in humans in vivo by increasing NO generation and explored whether the NO comes from the iNOS or eNOS isoform.
|
10435048 |
1999 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
IL-6 production is increased in gut mucosa during sepsis and endotoxemia and in cultured enterocytes after treatment with endotoxin or proinflammatory cytokines.
|
11975924 |
2002 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Treatment with IL-6, the main mediator of MT induction during endotoxemia, enhanced the expression of the MRE(d)-driven reporter gene.
|
11879976 |
2002 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
The IL-6 G(-174)C promoter polymorphism does not significantly influence basal concentrations of IL-6 or peak IL-6 in human endotoxemia.
|
14709647 |
2004 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Effect of interleukin-6 blockade on tissue factor-induced coagulation in human endotoxemia.
|
15190963 |
2004 |
Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
Quantification of IL-6 mRNA expression in circulating leukocytes is unlikely a suitable marker for monitoring of endotoxemia.
|
15721840 |
2005 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
RGD |
Protective effects of melatonin against the damages of neuroendocrine-immune induced by lipopolysaccharide in diabetic rats.
|
19449282 |
2009 |
Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
Reciprocal regulation of IL-6 and IL-10 balance by HGF via recruitment of heme oxygenase-1 in macrophages for attenuation of liver injury in a mouse model of endotoxemia.
|
19578789 |
2009 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
300 min after the proinflammatory insult, plasma concentrations of IL-1β and IL-6 in the plasma remain considerably lower after CLI compared to endotoxemia.
|
21296198 |
2011 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
RGD |
In vivo anticoagulant effect of ethyl pyruvate in endotoxemic rats.
|
21396682 |
2011 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Changes in blood glucose and glucose tolerance, plasma IL-6, triglycerides, and body temperature were characteristic of endotoxemia.
|
21914473 |
2011 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
RGD |
Application of thrombelastography in liver injury induced by endotoxin in rat.
|
22227956 |
2012 |
Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.
|
24681566 |
2014 |
Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
Treatment with both AGE and RGE in an in vivo experiment of LPS-induced endotoxemia significantly reduced the level of TNF-α and interleukin-6 in serum and completely protected against LPS-induced lethal shock in C57BL/6 mice.
|
25238199 |
2014 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
We aimed to assess in obese youths the relationships between interleukin-6 (IL-6), fat meal-induced endotoxemia and glucose homeostasis.
|
28216642 |
2017 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Opioid users also had higher endotoxemia and IL-6 but not IL-17.
|
27868217 |
2017 |
Endotoxemia
|
0.300 |
AlteredExpression
|
phenotype |
BEFREE |
It alleviated tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in activated macrophages by downregulating the NF-κB activity, and it reduced the mortality rate in LPS induced endotoxemia mice.
|
30297806 |
2018 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
At postoperative day 7, the sepsis-positive group continued to demonstrate an increase in intestinal permeability, endotoxemia and elastase; a significant difference was observed between the two groups (P = 0.02), whereas there was no significant difference in IL-1, IL-6, and CRP levels.
|
28803860 |
2018 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Finally, treating neonatal mice with IFNβ 2 h after endotoxemia stimulated pulmonary STAT1 signaling and STAT1 dependent gene expression.
|
30319651 |
2018 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
In addition, it resulted in the reduction of endotoxemia (through lipopolysaccharides (LPSs)) and pro-inflammatory cytokine (tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), and interleukin 1β (IL-1β)) levels, with the increased expression of tight-junction associated proteins (claudin-1, occludin, and zonula occludens-1).
|
30065236 |
2018 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Furthermore, leptin pre-treatment decreased the oxidative stress burst in blood and blunted the increased pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 observed during endotoxemia.
|
30618812 |
2018 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Furthermore, endotoxemia (LBP) was negatively correlated with serum testosterone but positively correlated with IL-6.
|
29183872 |
2018 |
Endotoxemia
|
0.300 |
Biomarker
|
phenotype |
BEFREE |
Furthermore, therapeutic studies in a systemic endotoxemia model demonstrated that mSPAM treatment reduced TNF-α and IL-6 inflammatory cytokines in serum, in turn circumventing organ damage done by the inflammatory macrophages.
|
30247915 |
2018 |