IL6, interleukin 6, 3569

N. diseases: 2367; N. variants: 22
Disease: Schnitzler Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524988
Disease: Schnitzler Syndrome
Schnitzler Syndrome 		0.020 AlteredExpression disease BEFREE Our findings do not support a role for somatic <i>NLRP3</i> mosaicism in disease pathogenesis; although elevated levels of ASC, IL-6, and IL-18 in patients' serum, and the response to anakinra, suggest that Schnitzler syndrome is associated with upregulated inflammasome activation. 29284595 2018
CUI: C0524988
Disease: Schnitzler Syndrome
Schnitzler Syndrome 		0.020 Biomarker disease BEFREE The use of anti-IL-6 mAbs showed promise as an alternative treatment in patients with Schnitzler syndrome. 23374612 2013