IL6ST, interleukin 6 signal transducer, 3572

N. diseases: 260; N. variants: 6
Disease: melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE Here, we compare OSM to the gp130-cytokine IL-6 in mediating macrophage polarization, and find that IL-6 overexpression alone (Ad vector, AdIL-6) did not induce Arg-1 protein in mouse lungs at day 7, nor ectopic melanoma tumor growth at day 14, in contrast to overexpression of OSM (AdOSM). 29363180 2018
CUI: C0025202
Disease: melanoma
melanoma 		0.030 PosttranslationalModification disease LHGDN Loss of oncostatin M receptor beta in metastatic melanoma cells. 16909117 2007
CUI: C0025202
Disease: melanoma
melanoma 		0.030 Biomarker disease BEFREE Two of the major protein species (gp88 and gp130) were common to all four cell lines used (HeLa-cervical carcinoma, T47D-breast carcinoma, and HMB2 and SK1477-two melanoma cell lines). 6093357 1984