IL6ST, interleukin 6 signal transducer, 3572

N. diseases: 260; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.030 Biomarker disease BEFREE It is valuable to explore the diverse actions of these gp130 cytokines on the regulation of the biological functions of adipocytes, which will provide potential therapeutic targets for the treatment of obesity and cachexia. 30661143 2019
CUI: C0028754
Disease: Obesity
Obesity
0.030 Biomarker disease BEFREE This review examines the potential role of gp130 receptor ligands as part of a therapeutic strategy to treat obesity. 17404609 2007
CUI: C0028754
Disease: Obesity
Obesity
0.030 GeneticVariation disease BEFREE We have evaluated the possible association of several polymorphisms in the IL6R-alpha and gp130 genes with obesity and/or hyperandrogenism in a case-control study involving 143 hyperandrogenic patients and 45 healthy women from Spain. 12917504 2003