IL7R, interleukin 7 receptor, 3575

N. diseases: 231; N. variants: 41
Disease: Promyelocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia 		0.020 AlteredExpression disease BEFREE The MAIT cells from the FGT and blood displayed a distinct phenotype with expression of interleukin (IL)-18Rα, CD127, α4β7, PD-1, as well as the transcription factors promyelocytic leukemia zinc finger (PLZF), RORγt, Helios, Eomes, and T-bet. 27049062 2017
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia 		0.020 AlteredExpression disease BEFREE Here, we show that Id2 also drives development of human ILC because forced expression of Id2 in human thymic progenitors blocked T cell commitment, upregulated CD161 and promyelocytic leukemia zinc finger (PLZF), and maintained CD127 expression, markers that are characteristic for human ILCs. 28912776 2017