CXCL8, C-X-C motif chemokine ligand 8, 3576

N. diseases: 1254; N. variants: 10
Disease: Fibrosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0016057
Disease: Fibrosarcoma
Fibrosarcoma 		0.020 Biomarker disease BEFREE Molecular analysis of the inhibition of interleukin-8 production by dexamethasone in a human fibrosarcoma cell line. 1592440 1992
CUI: C0016057
Disease: Fibrosarcoma
Fibrosarcoma 		0.020 GeneticVariation disease BEFREE Transfection of a human fibrosarcoma cell line with chloramphenicol acetyltransferase expression plasmids linked to a 5'-flanking deletion mutants of the IL-8 gene demonstrated that the nucleotides between -94 and -71 base pairs from the start of the first exon are essential and sufficient for the IL-8 induction by either IL-1, TNF, or phorbol 12-myristate 13-acetate. 2250017 1990