AQP1, aquaporin 1 (Colton blood group), 358

N. diseases: 226; N. variants: 5
Disease: Kidney Failure, Acute ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 Biomarker disease BEFREE Aquaporin-1 attenuates macrophage-mediated inflammatory responses by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury. 31529146 2019
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 Biomarker disease BEFREE These results suggest that urinary exosomal release of AQP1 and AQP2 is reduced in I/R-induced AKI, whereas that of Alix and TSG101 is increased in the initial phase of renal fibrosis. 29357442 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 Biomarker disease BEFREE The results of the present study suggest that AQP-1 may be an effective treatment for acute kidney injury caused by sepsis. 29731819 2018
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.040 Biomarker disease BEFREE In addition, they reduced molecular biomarkers of kidney injury such as KIM-1 and Cystatin C, while increased the markers of proximal tubular epithelium such as AQP-1 and CK18 following cisplatin-induced AKI. 28573544 2018