Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Viral infections, in particular EBV, HHV and HPV, have been shown to increase susceptibility to developing cancer, but also patients with defects in immune regulation, such as Autoimmune Lymphoproliferative Syndrome (ALPS), activated p110delta syndrome (APDS type 1) and IL-10 receptor deficiency among others have a higher incidence of neoplastic disease, particularly lymphomas.
|
31057537 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Our findings strongly indicate that IAV coinfection compromises the host's ability to control Mtb infection via the production of IL-10 which was rapidly induced upon viral infection.
|
30998505 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Interleukin (IL)-22, a member of the IL-10 family, plays a role in antiviral immune responses to a number of viral infections.
|
31344598 |
2019 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
In addition to type I IFN, expression of the anti-inflammatory cytokine IL10 was induced by viral infection before bacterial superinfection.
|
29881380 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Intact interleukin-10 receptor signaling protects from hippocampal damage elicited by experimental neurotropic virus infection of SJL mice.
|
29666403 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Thus, our findings elucidate a critical role for Tfh-derived IL-10 in promoting humoral immunity during persistent viral infection.
|
30487586 |
2018 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
A detailed immunological investigation of these patients revealed impaired responses to type I IFN, IL-10, IL-12 and IL-23, which are associated with increased susceptibility to mycobacterial and/or viral infections.
|
29725107 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Identification of IL-10-secreting CD8<sup>+</sup>CD28<sup>-</sup>PD-1<sup>+</sup> regulatory T cells associated with chronic hepatitis C virus infection.
|
30055200 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The detection of cytokines interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), interleukin-12 (IL-12), interleukin-4 (IL-4) and interleukin-10 (IL-10) indicates that NDV significantly induces Th1 responses and lowers Th2 responses.
|
29481983 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
NK cells are an important source of TGF-β and a main early producer of IL-10 in response to viral infection.
|
29439673 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
To date, many studies have shown that the production of inhibitory cytokines such as Interleukin 10 (IL-10), Transforming growth factor beta (TGF-β), along with dysfunction of the dendritic cells (DCs), and the absence of efficient innate immune responses could lead to T cell exhaustion, development of persistent infection, and inability to eradicate the viral infection from liver.
|
29273341 |
2018 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association of Single Nucleotide Polymorphisms in TNFA and IL10 Genes with Disease Severity in Influenza A/H1N1pdm09 Virus Infections: A Study from Western India.
|
30475169 |
2018 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Levels of IL-2, IL-8, and IL-10 on day 1 post-viral infection were significantly higher than those on day 1 post-bacterial infection.
|
27894819 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
IL-10 plays a decisive role in the course of persistent viral infection.
|
28263801 |
2017 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Here, we show that type I interferons (IFNs) are required for the development of IL-10-producing effector CD8<sup>+</sup> T cells during influenza virus infection in mice.
|
27701741 |
2016 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Effect of interleukin-10 gene promoter polymorphisms -1082 G/A and -592 C/A on response to therapy in children and adolescents with chronic hepatitis C virus infection.
|
27660094 |
2016 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
This study investigated genetic variability in the IL-10 gene promoter between patients infected with hepatitis C virus (HCV) and healthy individuals, associating the frequency of polymorphisms with different aspects of viral infection.
|
25797191 |
2015 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Association of interleukin-10 polymorphisms with chronic hepatitis C virus infection in a case-control study and its effect on the response to combined pegylated interferon/ribavirin therapy.
|
24641916 |
2015 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Whereas IL-10 is important in terminating pro-inflammatory and antiviral immune responses, the presence of this immune regulatory cytokine at the beginning of virus infection could impair the response to viruses and play a role in virus-induced asthma exacerbations.
|
25430775 |
2015 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
CD8+ Treg cells suppress CD8+ T cell-responses by IL-10-dependent mechanism during H5N1 influenza virus infection.
|
24114149 |
2014 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Mutations in IL10 were more frequently associated with bacterial and viral infections.
|
24216686 |
2013 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
Infected CD8α- dendritic cells are the predominant source of IL-10 during establishment of persistent viral infection.
|
22893686 |
2012 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
The role of IL-10 in regulating immunity to persistent viral infections.
|
20703965 |
2011 |
Virus Diseases
|
0.100 |
Biomarker
|
group |
BEFREE |
We aimed to evaluate the association among circulating IL-10, obesity phenotypes, IL-10 and IL-10R1 gene polymorphisms, and the environmental exposure to viral infection.
|
19798061 |
2010 |
Virus Diseases
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Interleukin-10 gene polymorphisms in association with susceptibility to chronic hepatitis C virus infection: a meta-analysis study.
|
20661604 |
2010 |