Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Human immunodeficiency virus (HIV) II infection category B1
0.100 Biomarker disease BEFREE Interestingly, correlations between Breg subsets (CD24hiCD27+ and PD-L1+ B cells) and IL-10-producing Breg observed in healthy individuals were lost in HIV+ treatment-naïve individuals. 30917149 2019
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE The results showed that pro-inflammatory cytokines: Tumour necrosis factor-alpha (TNF-α), Interleukin-6 (IL-6) and anti-inflammatory cytokines Interleukin-4 (IL-4), Interleukin-10 (IL-10) and Transforming growth factor-beta (TGF-β) were significantly elevated in HIV infected subjects before commencement of therapy compared to 6 months and 12 months into therapy (P < 0.01) and compared to control participants (P < 0.01). 30501642 2018
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE In response to Mtb antigens CFP-10 and ESAT-6, freshly isolated PBMCs from HIV+ LTBI+ and HIV+ active TB patients produced less IL-17 and IL-22 and more IL-10, expressed less IL-23R, and more PD1 and expanded to more FoxP3+ cells. 29996789 2018
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE Higher rates of unfavorable conditions, including lower education levels, IL-10 levels, and a trend for higher IFN-γ levels, were identified among HIV-infected women, pregnant and non-pregnant. 29513838 2018
Human immunodeficiency virus (HIV) II infection category B1
0.100 GeneticVariation disease BEFREE Detectable interleukin (IL)-1β (adjPRR = 2.14; 95% confidence interval (CI) = 1.02-4.48), IL-6 (adjPRR = 2.24; 95% CI = 1.28-3.90), IL-8 (adjPRR = 2.42; 95% CI = 1.15-5.08), IL-10 (adjPRR = 2.51; 95% CI = 1.67-3.80), and IL-13 (adjPRR = 1.87; 95% CI = 1.15-3.03) were associated with penile HIV shedding at the subsequent visit. 28011606 2017
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE In profiling of human genes from the same sputa, HIV-infected patients had 3.4-fold lower expression of IFNG (P = .005), 4.9-fold higher expression of ARG1 (P = .0006), and 3.4-fold higher expression of IL10 (P = .0002) than in HIV-uninfected patients with tuberculosis. 27534685 2016
Human immunodeficiency virus (HIV) II infection category B1
0.100 GeneticVariation disease BEFREE Interleukin-10 gene polymorphism (-1082G/A) and allergy to efavirenz in patients infected with human immunodeficiency virus. 24819158 2014
Human immunodeficiency virus (HIV) II infection category B1
0.100 Biomarker disease BEFREE Our studies demonstrate that blocking the signaling of these proinflammatory molecules in the DRG and/or the spinal cord using the HSV vector expressing IL-10 is able to reduce HIV-related NP. 25137003 2014
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE Human immunodeficiency virus (HIV) is characterized by immune activation, while chronic malaria is associated with elevated interleukin-10 (IL-10) levels. 23785209 2013
Human immunodeficiency virus (HIV) II infection category B1
0.100 GeneticVariation disease BEFREE IL-10-promoter polymorphisms have been shown to affect human immunodeficiency virus type 1 (HIV-1) clinical outcomes but the underlying mechanisms are poorly understood. 22100578 2012
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE We measured interferon (IFN)-gamma, tumour necrosis factor-alpha, transforming growth factor (TGF)-beta(1), interleukin (IL)-4, IL-10, IL-12p35 and IL-12p40 mRNA levels by real-time PCR performed on liver samples from HCV mono-infected (n = 19) and HCV/HIV co-infected (n = 24) patients. 18179452 2008
Human immunodeficiency virus (HIV) II infection category B1
0.100 Biomarker disease BEFREE The mucosal mRNA expression of TNF-alpha, IFN-gamma, IL-4, IL-6, and IL-10 was significantly higher in HIV-infected patients than in control patients and remained elevated during 9 months of HAART despite the decline in blood and mucosal HIV RNA levels and an increase in the level of CD4(+) T lymphocytes. 18573939 2008
Human immunodeficiency virus (HIV) II infection category B1
0.100 Biomarker disease BEFREE Enzyme-linked immunosorbent assay and/or reverse transcriptase PCR analysis showed higher levels of IL-4, IL-5, and IL-10 in the HIV-infected animals than in control hu-PBL-SCID mice, while gamma interferon levels in the two groups were comparable. 8892919 1996
Human immunodeficiency virus (HIV) II infection category B1
0.100 AlteredExpression disease BEFREE In contrast, the IL-10/BCRF1 gene expression was detected in only 1 out of 11 lymphomas from human immunodeficiency virus (HIV)-seronegative patients (p = 0.05). 1330578 1992