IL12B, interleukin 12B, 3593

N. diseases: 249; N. variants: 18
Disease: Parasitemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242723
Disease: Parasitemia
Parasitemia 		0.030 GeneticVariation disease BEFREE Higher parasitemia levels were observed in IL6-174C carriers (p=0.02) whereas IL12B CGT haplotype carriers presented lower parasitemia levels (p=0.008). 24139871 2014
CUI: C0242723
Disease: Parasitemia
Parasitemia 		0.030 GeneticVariation disease BEFREE Our data revealed that carriage of AA (P = 0.0001) and AC (P = 0.01) genotypes of IL12B 3'UTR polymorphism was associated with a significant increase of mean log-parasitemia relative to rare homozygous genotype CC. 23071570 2012
CUI: C0242723
Disease: Parasitemia
Parasitemia 		0.030 GeneticVariation disease BEFREE We cannot exclude that an unknown IL12B cis-regulatory element polymorphism affects both IL-12 production and parasitemia. 18449199 2008