IL15, interleukin 15, 3600

N. diseases: 426; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 Biomarker disease BEFREE Cell-Based IL-15:IL-15Rα Secreting Vaccine as an Effective Therapy for CT26 Colon Cancer in Mice. 31760731 2019
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 Biomarker disease BEFREE Treatment with a fusion protein of the extracellular domains of NKG2D to IL-15 retards colon cancer growth in mice. 24810637 2014
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 GeneticVariation disease BEFREE After controlling for multiple comparisons, single nucleotide polymorphisms (SNPs) from four genes, IL3, IL6R, IL8, IL15, were associated with increased colon cancer risk, and CXCR1 and CXCR2 were significantly associated with increased rectal cancer risk. 22674296 2013
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.040 AlteredExpression disease BEFREE Overall, the transient localized expression of IL-15 in the tumour by an oncolytic virus was able to induce stronger anti-tumoral immunity in a murine model of colon carcinoma. 22158521 2012