TNFRSF9, TNF receptor superfamily member 9, 3604

N. diseases: 177; N. variants: 9
Disease: Childhood Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.040 Biomarker disease BEFREE CD137 deficiency is a novel inborn error of human immunity characterized by lymphocytic defects with early-onset Epstein-Barr virus (EBV)-associated lymphoma. 31501153 2019
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.040 Biomarker disease BEFREE This inhibited CD8<sup>+</sup> T-cell responses to immune modulating antibodies, including anti-PD-1 and anti-4-1BB, resulting in less effective control of lymphoma. 29146881 2018
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.040 GeneticVariation disease BEFREE CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. 22308288 2012
CUI: C1332979
Disease: Childhood Lymphoma
Childhood Lymphoma 		0.040 Biomarker disease BEFREE We found that UCB-19BBzeta and UCB-28BBzeta T cells exhibited more cytotoxicity to CD19(+) leukemia and lymphoma cell lines than UCB-19zeta and UCB-1928zeta, although differences in secretion of interleukin-2 and interferon-gamma by these T cells were not evident. 19719389 2010