IL18, interleukin 18, 3606

N. diseases: 750; N. variants: 18
Disease: Hepatitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019158
Disease: Hepatitis
Hepatitis 		0.060 Biomarker group BEFREE Intestinal IL-17R Signaling Constrains IL-18-Driven Liver Inflammation by the Regulation of Microbiome-Derived Products. 31747600 2019
CUI: C0019158
Disease: Hepatitis
Hepatitis 		0.060 AlteredExpression group BEFREE Furthermore, Rg1 alleviated liver inflammation by inhibiting the activation of nucleotide binding oligomerization domain (NOD)-like receptor family pyrin domain-containing 3 (NLRP3) and thus reduced the production of inflammatory cytokines, such as interleukin 1-beta (IL-1β) and interleukin 18 (IL-18). 30135326 2018
CUI: C0019158
Disease: Hepatitis
Hepatitis 		0.060 Biomarker group BEFREE Severe liver inflammation and damage with elevated secretion of IL-1β and IL-18 were found in mice after HSCT. 26635145 2015
CUI: C0019158
Disease: Hepatitis
Hepatitis 		0.060 Biomarker group BEFREE To investigate the effects of intrasplenically transplanted fetal hepatocytes (BNL.CL2) transfected with recombinant adenovirus vector expressing the IL-18 binding protein (IL-18BP) and IL-4 fusion protein on ConA-induced hepatitis in mice. 23516562 2013
CUI: C0019158
Disease: Hepatitis
Hepatitis 		0.060 Biomarker group BEFREE Endotoxin-induced liver injury or Fas ligand-induced hepatitis is caused by endogenous IL-18 in mice. 14527086 2003
CUI: C0019158
Disease: Hepatitis
Hepatitis 		0.060 AlteredExpression group BEFREE Further, IL-18 expression in the HBx-transgenic liver, was correlated with the degree of hepatitis. 12175634 2002