IL18, interleukin 18, 3606

N. diseases: 750; N. variants: 18
Disease: Acute monocytic leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.030 GeneticVariation disease BEFREE We determined polymorphisms of NLRP3 (rs35829419), CARD8 (rs2043211), IL-1β (rs16944), IL-18 (rs1946518) and NF-κB -94 ins/del ATTG in de novo AML patients to find out whether they play roles in the susceptibility and severity of AML. 27928589 2017
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.030 Biomarker disease BEFREE In this study, we found that the abundances of the proinflammatory cytokine IL-18 and its receptor (IL-18R) correlated with the occurrence of drug resistance in AML patients during standard treatment. 26342105 2016
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.030 AlteredExpression disease BEFREE Clinical significance of IL-18 gene over-expression in AML. 12163048 2002