IL18, interleukin 18, 3606

N. diseases: 750; N. variants: 18
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE Intra-tumoral production of IL18, but not IL12, by TCR-engineered T cells is non-toxic and counteracts immune evasion of solid tumors. 29296541 2017
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE CAR T Cells Releasing IL-18 Convert to T-Bet<sup>high</sup> FoxO1<sup>low</sup> Effectors that Exhibit Augmented Activity against Advanced Solid Tumors. 29241547 2017
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE IL-18 protein was also found in 7/13 ovarian carcinoma solid tumors by immunohistochemic analysis. 11948465 2002