IL18, interleukin 18, 3606

N. diseases: 750; N. variants: 18
Disease: Acute Chest Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE We aimed to assess associations between circulating IL-18 concentrations and cardiovascular outcomes in patients with acute coronary syndromes (ACS). 31596518 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE Elevated IL-18 was associated with an increased likelihood of sweating in patients with ACS. 31238711 2019
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE The present study aimed to investigate associations between interleukin (IL)-6 and IL-18 and depression in patients with acute coronary syndrome (ACS) and potential interactions between statin use and pro-inflammatory cytokines on depression in this population. 28689006 2018
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE Both MMP-2 and IL-18 concentrations were increased in the ACS group compared to the SAP group or control group (P less than 0.01). 29685010 2018
CUI: C0742343
Disease: Acute Chest Syndrome
Acute Chest Syndrome 		0.050 Biomarker disease BEFREE The protein products of NLRP3 and CASP1 genes are involved in the cleavage of pro-IL-1B and pro-IL-18 leading to the active cytokines, which play an important role in the development of the acute coronary syndrome (ACS). 28456882 2017