IL18, interleukin 18, 3606

N. diseases: 750; N. variants: 18
Disease: Inflammatory dermatosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3875321
Disease: Inflammatory dermatosis
Inflammatory dermatosis 		0.030 Biomarker disease BEFREE Interleukin-18 exacerbates skin inflammation and affects microabscesses and scale formation in a mouse model of imiquimod-induced psoriasis. 30741833 2019
CUI: C3875321
Disease: Inflammatory dermatosis
Inflammatory dermatosis 		0.030 Biomarker disease BEFREE In this study, we investigated the effects of IL-18 on a psoriasis-like skin inflammation model induced by recombinant mouse IL-23. 28299442 2017
CUI: C3875321
Disease: Inflammatory dermatosis
Inflammatory dermatosis 		0.030 Biomarker disease BEFREE Because IL-18 directly stimulates T cells and mast cells to release AD-associated molecules, Th2 cytokines, and histamine, we investigated the capacity of IL-18 to induce AD-like inflammatory skin disease by analyzing KIL-18Tg and KCASP1Tg, which skin-specifically overexpress IL-18 and caspase-1, respectively. 12151598 2002