ILK, integrin linked kinase, 3611

N. diseases: 192; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.020 Biomarker group BEFREE AngII blockers are renoprotective and down-regulate ILK in experimental kidney disease, but the involvement of ILK in the actions of AngII in the kidney has not been addressed. 24383472 2014
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases
0.020 Biomarker group BEFREE We conclude that PINCH-1, through its interaction with ILK, plays an important role in regulating TGF-beta1-mediated EMT and could be a potential future therapeutic target to prevent progression of renal disease. 17656471 2007