IDO1, indoleamine 2,3-dioxygenase 1, 3620

N. diseases: 295; N. variants: 7
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.310 AlteredExpression disease BEFREE The pro-inflammatory state of obesity in pregnancy may drive activation of IDO-1, resulting in diversion of TRP away from serotonin and melatonin production and toward KYN metabolites. 29141444 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.310 Biomarker disease CTD_human Mice deficient in the tryptophan metabolizing enzyme indoleamine 2,3-dioxygenase 1 (IDO1) were also resistant to obesity. 27020609 2016