IDO1, indoleamine 2,3-dioxygenase 1, 3620

N. diseases: 295; N. variants: 7
Disease: Anhedonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.310 AlteredExpression disease BEFREE Our results show that six weeks post-LPS, mice present behavioral despair and anhedonia in association with increased IBA1 expression (a microglia activation marker), NF-kB p65 and IL-1β levels, indoleamine 2,3-dioxygenase (IDO1) mRNA expression, kynurenine, QUIN levels and QUIN/tryptophan ratio, and lowered tryptophan, 5-HT levels and SAT1 mRNA expression. 30326340 2018
CUI: C0178417
Disease: Anhedonia
Anhedonia 		0.310 Biomarker disease PSYGENET Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression. 22751107 2012