CXCL10, C-X-C motif chemokine ligand 10, 3627

N. diseases: 631; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE Immunomodulation of CXCL10 Secretion by Hepatitis C Virus: Could CXCL10 Be a Prognostic Marker of Chronic Hepatitis C? 31485460 2019
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 GeneticVariation disease BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE One of the multiple factors contributing to virological response in chronic hepatitis C (CHC) is interferon-gamma-inducible protein-10 (IP-10). 28862188 2017
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease BEFREE Correction of vitamin D deficiency facilitated suppression of IP-10 and DPP IV levels in patients with chronic hepatitis C: A randomised double-blinded, placebo-control trial. 28376103 2017
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE Association between CXCL10 and DPP4 Gene Polymorphisms and a Complementary Role for Unfavorable IL28B Genotype in Prediction of Treatment Response in Thai Patients with Chronic Hepatitis C Virus Infection. 26339796 2015
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE IP-10 Serum Level in Chronic Hepatitis C Virus Patients: Relation to Fibrosis and Response to Combined Interferon/Ribavirin Therapy. 25973761 2015
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 GeneticVariation disease BEFREE To assess the role of the ss469415590 variant, compared with the known IL28B polymorphisms (rs8099917, rs12979860 and rs12980275) for predicting virological response to therapy in chronic hepatitis C, and its association with the CXCL10 chemokine serum levels - a surrogate marker of interferon-stimulated genes activation. 24308755 2014
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE IP-10 in chronic hepatitis C patients treated with high-dose interferon. 25387553 2014
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease BEFREE Interferon (IFN)-γ-induced protein-10 (IP-10) serum level has been shown be associated with viral response in chronic hepatitis C (CHC) patients. 25263691 2014
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 GeneticVariation disease BEFREE Single nucleotide polymorphisms (SNPs) in IL28B and serum levels of interferon γ inducible protein 10 (IP-10) predict outcomes of antiviral therapy in patients with chronic hepatitis C. We associated IL28B SNPs rs12979860 and rs8099917, along with serum levels of IP-10, with outcomes of patients with acute hepatitis C (AHC). 22192885 2012
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE Chemokine CXCL10 at week 4 of treatment predicts sustained virological response in patients with chronic hepatitis C. 22799464 2012
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease BEFREE To determine the independent contribution of factors including IL28B polymorphisms, IFN-gamma inducible protein-10 (IP-10) levels and the homeostasis model assessment of insulin resistance (HOMA-IR) score in predicting response to therapy in chronic hepatitis C (CHC). 21443535 2011
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms. 21390311 2011
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease LHGDN Alpha-chemokine CXCL10 and beta-chemokine CCL2 serum levels in patients with hepatitis C-associated cryoglobulinemia in the presence or absence of autoimmune thyroiditis. 18702954 2008
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease BEFREE Increased serum and intrahepatic interferon gamma inducible protein 10 (IP-10) levels in patients with chronic hepatitis C (CHC) have been described. 16150856 2006
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 Biomarker disease BEFREE The data support the hypothesis that IP-10 is responsible for the recruitment of Th cells and monocytes in chronic hepatitis C, and suggest that its role in chronic hepatitis B is less determining. 12794718 2003
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease LHGDN The data support the hypothesis that IP-10 is responsible for the recruitment of Th cells and monocytes in chronic hepatitis C, and suggest that its role in chronic hepatitis B is less determining. 12794718 2003
CUI: C0524910
Disease: Hepatitis C, Chronic
Hepatitis C, Chronic
0.100 AlteredExpression disease BEFREE After successful treatment of AIH and chronic hepatitis C, the serum level of IP-10 decreased to the same level as in healthy volunteers. 11207658 2001