|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
Mice deficient in the myocyte channel aquaporin 7 (AQP7) show significantly reduced glycerol and ATP contents and develop obesity; however, the influence of AQP7 on cardioplegia effectiveness remains unclear.
|
31707553 |
2019 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
AQP7 is expressed in adipose tissue where it facilitates the efflux of glycerol, and AQP7 deficiency has been linked to increased glycerol kinase activity and triglyceride accumulation in adipose tissue, leading to obesity and secondary development of insulin resistance.
|
29300344 |
2018 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The present data suggest the promising therapeutic role of RKs in HF diet-induced obesity that is likely attributable, at least in part, to upregulation of AQP7 expression.
|
29787773 |
2018 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Adipocyte aquaporin 7 (AQP7) expression in lean children and children with obesity. Possible involvement in molecular mechanisms of childhood obesity.
|
30226208 |
2018 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
Aquaporin 7 (AQP7), a unique glycerol permeable integral membrane protein, has been associated with the onset of obesity.
|
28489425 |
2017 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
AQP7-deficient mice develop obesity, insulin resistance, and hyperglyceroluria.
|
22899094 |
2013 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
AQP7 is a glycerol channel in adipose tissue with a suggested role in controlling the accumulation of triglycerides and secondly development of obesity and type-2 diabetes.
|
23001483 |
2012 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
AQP7 transcript levels ratio of SAT vs. VAT changed with the presence of obesity and T2D.
|
20463097 |
2010 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The aim of the present work was to evaluate the effect of obesity and type 2 diabetes mellitus (T2DM) on gene expression levels of AQP7 in visceral adipose tissue (VAT) and AQP9 in liver.
|
18401671 |
2008 |
|
Obesity
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We examined whether common single nucleotide polymorphisms (SNPs) in the AQP7 gene modulate the risk of obesity and related abnormalities.
|
17351148 |
2007 |
|
Obesity
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Our objective was to test the hypothesis that AQP7 gene expression levels may be affected by presence of obesity and type 2 diabetes in humans.
|
17566090 |
2007 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
BEFREE |
New studies on AQP7 highlight the important role of glycerol transport in the development of obesity and metabolic disease.
|
16487720 |
2006 |
|
Obesity
|
0.400 |
Biomarker
|
disease |
CTD_human |
In summary, our data show that the AQP7 gene is differentially expressed in adipose tissue of lean and obese individuals.
|
16325777 |
2006 |