Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE The INT6 gene was originally identified as the insertion site of the mouse mammary tumor virus (MMTV), and later shown to be involved in human tumorigenesis. 28505193 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Our results suggest that EIF3E may have a role in the carcinogenesis of OSCC in non-betel quid chewers. 25123227 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Altered expression of the eukaryotic translation initiation factor 3 (eIF3) subunit eIF3e/INT6 has been described in various types of human cancer, but the nature of its involvement in tumorigenesis is not yet clear. 20453879 2010
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE Expression of truncated Int6/eIF3e in mammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis. 17626637 2007
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE These findings suggest potential integrated roles for INT6, TID1, and Patched proteins in cell growth, development, and tumorigenesis. 17385060 2007
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.060 Biomarker phenotype BEFREE The role of Int-6/eIF3-p48 in human carcinogenesis is unknown at the present time. 11115556 2001