Disease: Anemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia 		0.230 Biomarker disease BEFREE We generated mice with a cardiomyocyte-targeted deletion of Irp1 and Irp2 to explore the functional implications of ID in the heart independent of systemic ID and anaemia. 27545647 2017
CUI: C0002871
Disease: Anemia
Anemia 		0.230 Biomarker disease RGD IRP2 mRNA expression levels in the brain tissues were significantly decreased in the HI + anemia group compared with the HI group. 27602087 2016
CUI: C0002871
Disease: Anemia
Anemia 		0.230 Therapeutic disease RGD Effects of ferrous carbamoyl glycine on iron state and absorption in an iron-deficient rat model. 26584806 2015
CUI: C0002871
Disease: Anemia
Anemia 		0.230 Biomarker disease BEFREE Iron chelation, redistributing iron to the cytosol, might relieve IRP2 excess, improving heme synthesis and anemia. 17485548 2007
CUI: C0002871
Disease: Anemia
Anemia 		0.230 Biomarker disease BEFREE The physiological role of the IRP-IRE system is illustrated by (i) hereditary hyperferritinemia cataract syndrome, a human disease in which ferritin L-chain IRE mutations interfere with IRP binding and appropriate translational repression, and (ii) a syndrome of progressive neurodegenerative disease and anemia that develops in adult mice lacking IRP2. 16850017 2006