IRF1, interferon regulatory factor 1, 3659

N. diseases: 257; N. variants: 7
Disease: acute myeloid leukemia with multilineage dysplasia following myelodysplastic syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332153
Disease: acute myeloid leukemia with multilineage dysplasia following myelodysplastic syndrome
acute myeloid leukemia with multilineage dysplasia following myelodysplastic syndrome 		0.010 AlteredExpression disease BEFREE Accelerated exon skipping of IRF-1, resulting in transcripts lacking a translation initiation site, has been hypothesized as a means of functional inactivation of IRF-1 in AML/MDS. 10602416 1999