AQP9, aquaporin 9, 366

N. diseases: 100; N. variants: 4
Disease: Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 AlteredExpression group BEFREE This study investigated AQP9 expression in tumor tissues and defined the prognostic value in ccRCC patients. 31703694 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 Biomarker group BEFREE However, the role of AQP9 in regulating tumor sensitivity to adjuvant chemotherapy in colorectal cancer (CRC) has not been elucidated. 28640255 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 Biomarker group BEFREE The reduction of AQP3 by Auphen and increase of AQP9 by dbcAMP in nude mice suppressed tumor growth of HCC, which resulted in reduced AFP levels in serum and tissues, and apoptosis of tumor cells in the Auphen- and dbcAMP-treated mice, when compared with control mice (P < 0.01). 27022216 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 AlteredExpression group BEFREE In a human HCC SMMC-7721 cell line, over-expression of AQP9 suppressed cell invasion in vitro and xenograft tumor growth in vivo. 27216981 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 Biomarker group BEFREE These analyses suggested that AQP9 mRNA expression in glioblastoma is primarily explained by tumor infiltration with AQP9 expressing leukocytes. 24086629 2013
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 Biomarker group BEFREE The molecular mechanisms by which AQP9 affects the proliferation and apoptosis of astrocytic tumours need to be studied further. 18652774 2008
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.070 Biomarker group BEFREE In contrast, in human glioblastoma, most glioma cells throughout the tumor revealed a strong anti-AQP9 immunoreactivity across the whole surface of the cell. 17525633 2007