IRF2, interferon regulatory factor 2, 3660

N. diseases: 86; N. variants: 9
Disease: Leukemia, Myelocytic, Acute ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 AlteredExpression disease BEFREE IRF2 and INPP4B were highly expressed in AML cell lines, and were positively correlated with autophagy-related proteins. 30876449 2019
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 Biomarker disease BEFREE In conclusion, IRF2 serves as an important regulator in AML by targeting INPP4B. 28579269 2017
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 AlteredExpression disease BEFREE Clinically, approximately 70% of cases of acute myeloid leukaemia demonstrate dysregulated expression of IRF1 and/or IRF2. 18575764 2008
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.040 AlteredExpression disease BEFREE Alterations in IRF1/IRF2 expression in acute myelogenous leukemia. 11559933 2001