IRF3, interferon regulatory factor 3, 3661

N. diseases: 174; N. variants: 9
Disease: Bacterial Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.030 Biomarker group BEFREE Controversial data exist regarding the role of IRF3 in immune cell recruitment during bacterial infections. 28181039 2017
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.030 Biomarker group BEFREE Nuclear translocation of IRF3 was significantly increased in ITSCs and slice cultures treated with lipopolysaccharide (LPS) and 1,8-cineole compared with the LPS-treated cells mimicking bacterial infection. 27129189 2016
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.030 Biomarker group BEFREE We found that the efficient and self-limiting innate immune response to bacterial infection relies on a tight balance between IRF-3 and IRF-7. 27122612 2016